6) Occupational causes
Occupational causes of knee osteoarthritis include prolonged standing, repetitive bending, and heavy lifting. These activities can cause excessive stress on the knee joint and lead to the breakdown of cartilage.
This repetitive activity causes friction and triggers the release of inflammatory substances, such as cytokines, which can further damage the joint and increase pain and stiffness. Over time, these changes can lead to joint instability, loss of range of motion, and, in severe cases, disability.